Mass Effect 3 releases soon. That being said, please be careful to mark all spoilers!
FemShep is clearly the better voice actress, but I couldn't play her because my friends would make fun of me. Nurhurhur
This is one of the few game (series), in my opinion, that actually makes a workable morality scale. Being Renegade doesn't mean you shoot civilians just because you're grumpy, and your not out just to kick puppies. It just means you're willing to do what needs to be done, consequences be damned.
Paragon is, of course, the goody-two-shoes counter to Renegade, and plays out about as stereotypically as you'd expect the 'Good' side of the 'Good vs Evil' scale would.
While the first game has massive RPG elements, with multiple skills each having their own tree, equipment coming in a variety of shapes, sizes, and functions, the second game streamlines much of this and simplifies everything. You can still tweak your gear to fit your playstyle, but the inventory management is almost completely gone. Rather than buying pieces of armor, new guns, and mods for both, you simply research the benefits for the equipment you want, or buy the upgrades from NPCs.
Current topic of discussion; did the inclusion of thermal clips influence your class choice going from ME1 to 2?
In ME1, I started as an Adept (use of biotics), but stopped shortly after starting. The power management for biotic powers was a little clunky in the first game, especially since you can only hotkey one skill at a time. Instead I swapped to Infiltrator and sniped things at my leisure, modding my sniper rifle to have outrageous damage while overheating at the first shot. Lots of fun!