No one is the Bond girl and everyone is the Bond villain. The plot is just them making the life of that miserable, insufferable cur utter and complete hell, intentionally or not, from Reimu sweeping his ass down the stairs of the shrine to Marisa setting his tux on fire to Seija inverting the flow of his intestines to Eirin skewing him with arrows to Unzan and Yuugi breaking his arms in a succession arm-wrestling matches to Rinnosuke selling him crappy gadgets that fail at crucial moments to Yukari just gapping him back to the outside world at the very bottom of the Mariana Trench.
That'd probably be the second Bond anything I'd actually enjoy. Haha, yeah...
I might be wrong but i get the feeling you aren't a great admirer of Bond.... :V (And now i'm curious which would be the FIRST Bond thing you enjoyed.....)
Speaking of the topic, here is my personal cast:
Bond Girl = Suwako (first, it would be HILARIOUS to have a loli-among-lolis as Bond Girl; second, considering they always ends up in bed i think the only confirmed non-virgin is best suited for the role :derp:)
Bond Villain = Yukari (i can totally see her getting interested in messing around with this weird human, and messing around with Bond is practically the MO of Bond villains....)
Q = Nitori. Really, who else? :]
M = Kasen (serious, lecture-happy, but well-meaning..... Eiki would be the same but she'd balk at the amount of BLACK in Bond's life)